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Product capability: TLC

Linomat 5 Hero

CAMAG® Linomat 5

Written by Admin Camag on .

CAMAG®
Linomat 5

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In a nutshell

Experience Precision and Reproducibility

The CAMAG Linomat 5 provides precise and reproducible sample application, ensuring reliable results for a wide range of TLC workflows. Its semi-automatic design allows for both standalone operation and seamless integration with CAMAG’s visionCATS software, offering flexibility for different analytical needs.

The Linomat 5 applies samples as narrow, uniform bands using a spray-on technique powered by compressed air or nitrogen. This method enhances separation quality and resolution while minimizing sample and solvent consumption.

The Linomat 5 is optimized for efficient and consistent performance, making it suitable for applications in pharmaceuticals, food safety, environmental monitoring, and more.

  • Semi-automatic application
  • Application of spots or bands
  • Any plate format up to 20 x 20 cm
  • Spray-on application
  • Data input through visionCATS software or keypad
HPTLC fingerprint

SPRAY-ON APPLICATION AS BANDS

HPTLC fingerprint (flavonoids) of green and black tea samples representing different geographic origins, applied with the CAMAG Linomat 5.

hptlc fingerprint

HPTLC fingerprint (flavonoids) of green and black tea samples representing different geographic origins.

Track assignment (tracks taken from different plates)

  • Track

    Details

  • 1

    Reference substances with increasing RF: rutin, chlorogenic acid, hyperoside, gallic acid

  • 2 – 8

    Green tea from China

  • 9 – 13

    Green tea from Japan

  • 14 – 15

    Green tea from India

  • For comparison

  • 16 – 17

    Black tea from Sri Lanka
HOW IT WORKS

Operation of the CAMAG Linomat 5

  • visioncats-hptlc-made-easy

    01

    The Linomat 5 is operated by visionCATS HPTLC software, offering easy and convenient instrument handling. Simply select a plate format, fill in the sequence table and start working. With visionCATS, the Linomat 5 can be IQ/OQ qualified and used in a cGMP environment.

  • CAMAG Linomat 5_syringe_02

    02

    The sample liquid is sprayed onto the layer from the tip of the syringe needle. The stage movement is controlled so that the sample is uniformly distributed over the entire length of the band. Samples can also be sprayed-on as spots.

  • CAMAG Linomat 5_frontal_detail_03

    03

    The combination of the special dosage syringe with the spray nozzle of the Linomat 5 ensures the focused spraying-on of samples on very small areas.

  • CAMAG Linomat 5_object_support_04

    04

    The self-adjusting object support enables application onto objects of variable thickness (up to 4 mm) without any adjustment to the spray nozzle. This makes it easy to change between conventional TLC and HPTLC layers (on glass plates or sheets), preparative layers and very thin objects such as membranes. The support accommodates objects up to 20 x 20 cm.

  • CAMAG Linomat 5_visioncats-report

    05

    All data of the current analysis (e.g. information on the chromatogram layout, solvents used, dosage speed or application volumes) is saved by the visionCATS HPTLC software in a report file.

Technical specifications

General data

  • Object support
    For objects up to 20 x 20 cm
  • Stage drive
    Stepping motor 3200 steps/rotation, 8 steps = 0.1 mm Band length 0 (spot) – 190 mm in steps of 0.1 mm Speed approx. 10 mm/s; the speed is automatically adapted such that a whole number of passages is reached with the volume selected.
  • Dosage syringe drive
    Stepping motor 1600 steps/rotation 100 nL = 120 steps with 100 µL syringe 100 nL = 24 steps with 500 µL syringe
  • Sample dosage syringe
    selectable 100 µL or 500 µL
  • Memory
    10 methods, backup min. 10 years
  • LCD display
    2 lines of 16 characters ea.
  • Power connection
    85–250 V~ 47–63 Hz 30 VA
  • Gas supply
    4–6 bar (60–90 PSI) preferably nitrogen; consumption approx. 1.0 L/min
  • Dimensions (W x D x H)
    360 x 510 x 410 mm
  • Weight
    12.5 kg

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CAMAG NANOMAT 4

CAMAG® Nanomat 4

Written by Admin Camag on .

CAMAG®
Nanomat 4

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In a nutshell

Manual Sample Application for TLC Analysis

The Nanomat 4 is a reliable instrument designed for precise and reproducible sample application onto TLC plates, ensuring uniform distribution for high-quality results. It provides flexibility for a wide range of sample volumes, making it suitable for research and routine analysis.

Equipped with a spring-loaded mechanism, the Nanomat 4 applies controlled pressure to prevent plate damage, ensuring smooth sample transfer. Its user-friendly design makes it easy to operate, saving time and reducing errors in the lab.

The Nanomat 4 is ideal for applications in pharmaceuticals, food testing, cosmetics, and environmental analysis, delivering consistent and accurate results essential for quality control and impurity testing.

Its precision, versatility, and ease of use make the Nanomat 4 an indispensable basic tool for any lab conducting TLC analysis.

  • Manual sample application
  • For plates up to 20 x 20 cm
  • Application of spots by contact transfer
  • Disposable capillary pipette
  • Precise positioning to apply a defined pattern

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CAMAG SMARTCUT

CAMAG® smartCut

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CAMAG®
smartCut

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In a nutshell

Effortless Precision Cutting

The CAMAG® smartCut is a precision instrument designed for the convenient and accurate cutting of pre-coated TLC and HPTLC glass plates into defined pieces of any format. It accommodates glass plates up to 3 mm thick, ensuring smooth edges without damaging the sensitive layer.

The device features an integrated scale for easy measurement of desired sizes, facilitating precise cuts and reducing material waste. Its user-friendly design enhances laboratory efficiency, making it an essential tool for chromatographic applications.

  • Cuts glass plates with a thickness up to 3 mm
  • Easy on the sensitive layer
  • Desired size can be read directly from a scale
  • Prevents offcuts and thus saves money
  • Easy handling

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HPTLC Plates

TLC Plates

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CAMAG®
TLC Plates

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In a nutshell

Versatile TLC Plates for Reliable Analysis

CAMAG offers a comprehensive selection of thin-layer chromatography (TLC) plates, pre-coated with high-quality sorbent materials on glass or aluminum supports, to meet diverse analytical requirements. 

Utilizing these TLC plates facilitates efficient, reproducible, and high-resolution separations, making them indispensable tools for qualitative and quantitative analyses across various industries.

To learn more about Merck TLC plates, please visit Merck and Sigma-Aldrich.

  • Pre-coated TLC plates on a support of glass or aluminum
  • Silica gel 60 or RP-18 with F254
  • Layer thickness 200 or 250 µm
  • Available in the formats 10 x 20 cm or 20 x 20 cm

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multipurpose-spotting-guide_800x800

CAMAG® Multipurpose Spotting Guide

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CAMAG®
Multipurpose Spotting Guide

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In a nutshell

Accurate Manual Sample Application

The CAMAG® Multipurpose Spotting Guide is an essential tool for setting up chromatograms on standard 20 × 20 cm TLC plates. It features a grooved ruler that allows for precise manual positioning of capillaries, ensuring accurate and reproducible sample application. This guide can be used in conjunction with the Capillary Dispenser system, such as the CAMAG® Nanomat 4, to facilitate convenient manual sample application. By providing consistent sample spots, it enhances the reliability of chromatographic analyses, making it a valuable asset in any laboratory performing thin-layer chromatography.

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CAMAG® Twin Trough Chamber

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Twin Trough Chamber

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In a nutshell

Consistent Results, Minimal Solvent Use

This is a classical developing tank for Thin-Layer Chromatography. Compared to a Flat Bottom Chamber less solvent is needed. A Twin Trough Chamber reduces disposal problems and allows preconditioning of the plate with any solvent and for any duration. For preconditioning or saturation the trough opposite to the plate is filled with developing solvent. The use of a saturation pad is recommended for a fast, homogeneous and reproducible chamber saturation process.

  • Glass tank with two troughs for manual development
  • Available for 20 x 10 cm, 20 x 20 cm, and 10 x 10 cm plates
  • Steel or glass lid

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CAMAG® Flat Bottom Chamber

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Flat Bottom Chamber

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In a nutshell

NEW STANDARD OF REPRODUCIBILITY

This is a classical developing tank for Thin-Layer Chromatography. Compared to a Twin-Trough-Chamber more solvent is needed. Also a Twin-Trough-Chamber reduces disposal problems and allows preconditioning of the plate with any solvent and for any duration.

  • Glass tank with flat bottom for manual development
  • Available in the formats 20 x 20 cm and 10 x 10 cm
  • Steel or glass lid

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